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Double Four-Effect Evaporator for Pharmaceutical Industry, GMP Standard, 304 SS

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Product Spotlights

GMP-compliant double four-effect evaporator made of 304 SS for pharmaceutical concentration. Energy-efficient design reduces steam consumption by up to 40%. Customizable capacity, sanitary construction, PLC control, and comprehensive documentation support validation.
US$ 4260 - 785000 MOQ: 1 Combo
Key Specifications
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Type:
Other, Double Four-Effect Evaporator
Material:
304 Stainless Steel
Standard:
GMP Compliant
Payment & Shipping
Payment Methods:
Port of Shipment:
Qingdao
Delivery Detail:
90 days
Type Other, Double Four-Effect Evaporator
Material 304 Stainless Steel
Standard GMP Compliant
Application Pharmaceutical Industry
Capacity Customizable (available upon request)
Configuration Four-effect evaporation system
Operation Continuous or batch
Surface Finish Mirror polished (Ra ≤ 0.4 μm optional)

Qingdao Conqinphi Environmental Technology Group Co., Ltd. proudly presents our Double Four-Effect Evaporator designed specifically for the pharmaceutical industry. Manufactured in our 10,000-30,000 m² facility since 2015, this evaporator embodies our commitment to precision engineering and process safety. Constructed from 304 stainless steel and complying with GMP standards, it delivers exceptional concentration efficiency while maintaining product purity—critical for pharmaceutical intermediates and APIs. With annual export value exceeding US$10 million and a team of 201–300 skilled professionals, we ensure every unit meets rigorous quality benchmarks.

This evaporator utilizes a double four-effect design to maximize energy recovery and minimize steam consumption. The four-effect configuration allows for progressive concentration, reducing thermal degradation of heat-sensitive pharmaceutical compounds. The entire system is built with sanitary welds, smooth surfaces, and easy-clean features that support CIP/SIP protocols, making it ideal for sterile and high-purity environments.

Key Features & Technical Specifications

  • Double Four-Effect Design: Four evaporation stages arranged in series, with each stage recovering heat from the previous stage, delivering up to 40% energy savings compared to single-effect evaporators.
  • 304 Stainless Steel Construction: All wetted parts are made of 304 SS, providing excellent corrosion resistance and compatibility with a wide range of pharmaceutical solvents and solutions.
  • GMP-Compliant Fabrication: Smooth internal surfaces (Ra ≤ 0.6 μm standard, optional
  • Advanced Control System: PLC-based automation with touchscreen interface, monitoring temperature, pressure, feed rate, and concentrate density in real time.
  • Modular & Compact Footprint: Pre-assembled skid-mounted design reduces installation time and floor space requirements.
  • Multiple Safety Features: Overpressure protection, vacuum break valves, and emergency shutdown system.

Parameter Value
Number of Effects 4 (double four-effect configuration)
Material of Construction 304 Stainless Steel
Evaporation Capacity 500 – 10,000 L/h (customizable)
Operating Temperature 40°C – 120°C (adjustable)
Steam Consumption ~0.25 kg steam per kg water evaporated (typical)
Electrical Supply 380V/50Hz or as per local requirement
Control System PLC + HMI (Siemens or equivalent)

Benefits for Your Pharmaceutical Production

  • Higher Product Quality: Gentle evaporation at lower temperatures preserves heat-sensitive active ingredients, reducing degradation and improving yield.
  • Lower Operating Costs: The four-effect heat recovery system cuts steam usage by up to 40%, resulting in significant annual savings.
  • Easy Cleaning & Validation: Smooth welds, sloped bottoms, and CIP-compatible design simplify cleaning validation, reducing downtime between batches.
  • Scalable & Flexible: Available in multiple capacity ranges, with options for vacuum operation, forced circulation, or falling film configuration to match your specific process.
  • Compliance Ready: Designed to meet GMP guidelines, with full documentation including IQ/OQ protocols, material certificates, and surface finish reports.

Trust Built on Experience

As a manufacturer with over 8 years of expertise, Qingdao Conqinphi Environmental Technology Group has supplied evaporators to clients across North America, Europe, Southeast Asia, and the Middle East. Our factory spans 10,000–30,000 m² and houses advanced fabrication equipment, including automated welding, surface polishing, and pressure testing rigs. We hold multiple management system certifications (ISO9001, ISO14000, OHSAS18001, etc.) and follow strict quality control procedures. Each Double Four-Effect Evaporator undergoes rigorous inspection, including hydrostatic testing, surface finish verification, and performance trials before shipment.

Our team of 201–300 employees includes experienced process engineers, welders, and project managers who work closely with clients to tailor the evaporator to their specific requirements. From initial design to after-sales support, we provide comprehensive service. We ship from Qingdao port, ensuring efficient logistics to global destinations.

Ready to optimize your pharmaceutical concentration process? Contact us today to discuss your capacity, solvent type, and concentration needs. We will provide a customized proposal with detailed technical drawings, a competitive price, and a clear delivery timeline.

Frequently Asked Questions

Q1: What is the difference between a double four-effect evaporator and a standard four-effect evaporator?

A: The term "double four-effect" sometimes refers to a configuration where two parallel streams of four-effect evaporation are combined, or it can indicate a system with four effects but designed with double the heating surface area per effect. In our design, it means a robust four-effect system optimized for high-capacity pharmaceutical applications, providing enhanced heat recovery and redundancy.

Q2: Can this evaporator handle viscous or fouling liquids?

A: Yes, we can customize the design with forced circulation or scraped surface options to handle viscous or fouling fluids. The standard falling film configuration works well for low-to-medium viscosity solutions. Please provide your fluid properties for a tailored recommendation.

Q3: What certifications does the evaporator come with?

A: The evaporator is manufactured under ISO9001 quality management system. It is designed to meet GMP standards. We can provide material certificates (MTC), welding procedure qualification records (WPQR), and pressure test reports. Specific third-party certifications (e.g., ASME, PED) are available upon request at additional cost.

Q4: What is the typical lead time?

A: For standard models, lead time is 60–90 days after confirmation of order and technical specifications. Customized units may require 90–120 days, depending on complexity.

Q5: Does the system include a vacuum pump?

A: Yes, the evaporator can be supplied with a vacuum pump (liquid ring or dry screw) to create the required vacuum for low-temperature evaporation. Please specify your desired vacuum level or whether you want us to recommend based on your process.

Q6: How do you ensure the surface finish meets GMP requirements?

A: We use mechanical polishing and electropolishing techniques to achieve surface roughness Ra ≤ 0.6 μm as standard, with optional Ra ≤ 0.4 μm. Each surface is inspected with a profilometer, and records are provided in the documentation package.

Q7: What after-sales support do you offer?

A: We provide 12-month warranty, online technical support, spare parts availability, and optional on-site commissioning assistance. Our global service network ensures timely response.

Q8: Can I visit your factory or request a reference list?

A: Absolutely. We welcome factory inspections and can arrange visits to our Qingdao facility. We can also share references of similar evaporators supplied to pharmaceutical companies, subject to confidentiality agreements.

Product Tags: Double Four-Effect Evaporator , Pharmaceutical Evaporator GMP , 304 SS Multi-Effect Evaporator

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Gold Verified Supplier
1Yr
Verified Business License
Business Type
Manufacturer
Year Established
2015
Factory Size
10,000-30,000 square meters
Annual Export Value
US$10 Million - US$50 Million