Plethysmometer

LABAIDS Digital Plethysmometer is a micro-controlled volume meter, specially designed for highly accurate measurement of the rat/mouse paw swelling.

The Digital Plethysmometer is designed to provide a highly useful tool in the measurement of small volume changes. This test is typically used to follow the evaluation of the inflammatory response experimentally induced in rodents and to screen potential anti-inflammatory or anti-oedema properties of pharmacological substances. The water displacement produced by the immersion of the animal paw in the measuring tube is reflected into the second tube, inducing a change in the conductance between the two platinum electrodes. The Plethysmometer Control Unit detects the conductance changes and generates an output signal to the digital display indicating the volume displacement measured. The current value remains in the digital display until a new trial starts. The Control Unit can be zeroed between successive readings by pressing the ZERO button, so that the error arising due to adherence of water.