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Qingdao Conqinphi Environmental Technology Group Co., Ltd. is a professional manufacturer established in 2015, with a factory area of 10,000-30,000 square meters and over 200 experienced employees. Our Pharmaceutical Grade Multi-effect Evaporation and Concentration of Mannitol for Injection Production is designed to meet the highest standards of purity and efficiency in the pharmaceutical industry. This advanced system utilizes multi-effect evaporation technology to concentrate mannitol solutions under controlled vacuum conditions, ensuring minimal degradation and maximum product quality. With annual export value exceeding US$10 million, we serve global markets including North America, Europe, and Asia, providing reliable solutions for injection-grade mannitol manufacturing.
Our equipment is built with stainless steel 316L construction, offering excellent corrosion resistance and compatibility with pharmaceutical environments. The multi-effect design significantly reduces energy consumption by reusing vapor from one effect to heat the next, achieving up to 70% energy savings compared to single-effect evaporators. Each unit is equipped with a PLC-based automatic control system, allowing precise adjustment of temperature, vacuum, and feed rate to ensure consistent product concentration and quality. Below is a summary of key technical parameters:
| Parameter | Specification |
|---|---|
| Evaporation capacity | 500 - 5000 kg/h (customizable) |
| Number of effects | 3 - 7 effects (optional) |
| Operating temperature range | 60°C - 100°C |
| Vacuum level | 0.01 - 0.1 MPa |
| Heating source | Steam or thermal oil (optional) |
| Material of construction | Stainless steel 316L |
| Control system | PLC with touch screen, automatic operation |
Product Features and Benefits:
- Pharmaceutical-grade design: All contact surfaces are polished to Ra ≤0.4μm, preventing bacterial growth and ensuring compliance with GMP requirements.
- Low-temperature concentration: Vacuum operation reduces boiling point, preserving thermolabile components of mannitol and maintaining high purity for injection use.
- Energy-efficient multi-effect system: Each additional effect reduces steam consumption by approximately 30-40%, lowering operational costs.
- High recovery rate: Integrated solvent recovery system (optional) captures condensate with >99% efficiency, minimizing waste.
- Automated CIP/SIP: Clean-in-place and sterilize-in-place options are available for easy maintenance and contamination prevention.
- Customizable capacity: From laboratory-scale (500 kg/h) to industrial-scale (5000 kg/h) units, tailored to your production volume.
- Safety features: Over-pressure protection, temperature alarms, and emergency shutdown ensure safe operation.
Our manufacturing facility is certified under ISO9001, ISO14001, and OHSAS18001, reflecting our commitment to quality, environmental management, and occupational health. With a dedicated team of 201-300 employees, we have supplied evaporation systems to pharmaceutical companies across 20+ countries. The main markets include North America, South America, Europe, and Asia, and we have successfully delivered projects for injection-grade mannitol production lines.
Trust and After-Sales Support: We provide comprehensive technical documentation, installation guidance, and 24/7 technical support. Our after-sales team is available for remote troubleshooting and on-site service if required. The equipment is shipped from Qingdao Port with careful packaging to ensure safe transport. We also offer a 12-month warranty on all components and extended service contracts upon request.
Frequently Asked Questions (FAQ)
-
What is the typical concentration ratio achievable for mannitol solutions?
Our multi-effect evaporator can concentrate mannitol from 10-15% initial solids to 60-70% final concentration, depending on the viscosity and temperature requirements. The exact ratio can be customized based on your process. -
Can this equipment handle other pharmaceutical ingredients besides mannitol?
Yes, the system is designed for multi-purpose use and can be used for concentration of various heat-sensitive pharmaceutical solutions such as glucose, fructose, and amino acids, provided the material is compatible with stainless steel 316L. -
What is the required steam pressure for operation?
Typically, saturated steam at 0.2-0.6 MPa is sufficient. For thermal oil heating, the temperature range is 100-200°C. We can adjust the design to match your utility supply. -
How do you ensure the equipment meets GMP standards?
The equipment is manufactured with smooth surfaces, no dead legs, and materials approved for pharmaceutical contact. We provide a material certificate, weld logs, and an IQ/OQ documentation package upon request. -
What is the lead time for delivery?
Standard lead time is 45-60 days after order confirmation, depending on the configuration and capacity. Expedited orders may be available with a surcharge. -
Do you offer on-site installation and commissioning?
Yes, we can provide an engineer for on-site installation and commissioning at an additional cost. Alternatively, we offer remote guidance via video call. -
What certifications are included with the equipment?
The equipment is manufactured in an ISO9001 certified facility. We can provide CE marking or other certifications upon request (subject to third-party assessment). -
Can the solvent recovery system be integrated?
Yes, an optional vapor condensate recovery system can be added to reclaim water or organic solvents, reducing waste and operating costs.
Choose Qingdao Conqinphi for your Pharmaceutical Grade Multi-effect Evaporation and Concentration of Mannitol for Injection Production – a reliable partner with proven expertise, global reach, and a commitment to quality. Contact us today to discuss your requirements and request a customized quotation.
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