Precision Filter for Pharmaceutical Water Treatment, 0.22 Micron, Sanitary Clamp Connection
Product Spotlights
Precision Filter for Pharmaceutical Water Treatment – manufactured by Anping County Boli Hardware Wiremesh Products Factory, a trusted manufacturer since 1998 with annual export value exceeding US$5 million and serving markets across North America, South America, Europe, Asia, Africa, and Oceania. Our 0.22 micron sanitary clamp filter is designed to meet the demanding requirements of pharmaceutical water systems, providing reliable microbial removal and consistent performance. With over two decades of experience in filtration solutions, we deliver precision-engineered filters that ensure purity and safety in critical applications.
Key Features & Technical Specifications
- 0.22 Micron Absolute Filtration – Effectively removes bacteria, yeast, mold, and particulate matter, ensuring compliance with pharmaceutical water quality standards (e.g., USP , EP for Purified Water and WFI).
- Sanitary Clamp Connection – Tri-clamp design allows quick, hygienic installation and removal without tools, reducing contamination risk and downtime.
- High-Quality PTFE Membrane – Hydrophobic or hydrophilic options available; low protein binding, high flow rates, and excellent chemical resistance for steam sterilization (autoclavable).
- Stainless Steel Housing – 304L or 316L SS construction, electropolished surfaces (Ra ≤ 0.5 μm) for easy cleaning and validation.
- Wide Temperature & Pressure Range – Operates up to 85°C (185°F) and 4.0 bar (58 psi) at 25°C; suitable for continuous hot water circulation.
- Multiple Lengths Available – Standard sizes: 10”, 20”, 30”, with custom lengths upon request to fit existing housings.
- Integrity Testable – Compatible with bubble point, diffusion, or pressure hold tests for in-situ validation.
- ISO 9001 Quality Management – Manufactured under controlled processes (note: specific certification not confirmed; factory follows strict internal quality standards).
Technical Parameters
| Parameter | Value |
| Filtration Grade | 0.22 μm (absolute) |
| Filter Media | PTFE (Polytetrafluoroethylene) |
| Housing Material | 304L / 316L Stainless Steel |
| Connection | Sanitary Clamp (1.5” – 4” available) |
| Length | 10”, 20”, 30” (customizable) |
| Max. Operating Temperature | 85°C (185°F) |
| Max. Differential Pressure | 4.0 bar (58 psi) at 25°C |
| Sterilization | Autoclavable at 121°C / 134°C (30 min) |
| Applications | WFI, Purified Water, Buffer Solutions, Water for Injection |
Advantages for Your Pharmaceutical Water System
- Enhanced Product Safety – The 0.22 micron retention ensures sterility and prevents microbial contamination in final drug products.
- Reduced Operational Costs – High dirt-holding capacity and long service life (typically 6–12 months depending on feed water quality) minimize replacement frequency.
- Ease of Validation – Compatibility with standard integrity test methods simplifies regulatory compliance (FDA, EU GMP, WHO).
- Hygienic Design – Sanitary clamp connections eliminate dead legs and allow fast, safe change-out; electropolished surfaces prevent biofilm formation.
- Customization Options – Available in different lengths, end configurations (222 O-ring, 226 O-ring, etc.), and membrane types (hydrophobic for venting, hydrophilic for aqueous).
- Global Supply Chain – Shipped from Tianjin, Qingdao, Shanghai, or Foshan ports with reliable logistics; supported by our 20+ year export experience.
Trust in Our Proven Track Record – Since 1998, Anping County Boli Hardware Wiremesh Products Factory has been a dedicated manufacturer of filtration products. With annual exports between US$5 million and US$10 million and a presence in major markets including North America, Europe, Southeast Asia, and the Middle East, we have earned the confidence of pharmaceutical companies worldwide. Our factory in Hengshui, Hebei, China, is equipped with modern production lines and rigorous quality control procedures. We are committed to providing reliable, compliant, and cost-effective filtration solutions. Contact us today to request a sample, discuss your specific dimensions, or receive a competitive quotation. Let us be your partner in achieving water purity excellence.
Frequently Asked Questions (FAQ)
- What is the material of the filter membrane? – The membrane is made of PTFE (polytetrafluoroethylene), which offers excellent chemical resistance and low extractables. Both hydrophobic and hydrophilic variants are available.
- Can this filter be steam sterilized? – Yes, the filter can be autoclaved at 121°C or 134°C for 30 minutes, or steam-in-place (SIP) if properly installed in a housing.
- What is the typical flow rate for a 10-inch element? – Flow rate depends on pressure and water quality. For clean water at 1 bar differential pressure, a 10-inch element typically delivers 5–15 L/min. Contact us for a detailed sizing calculation based on your system.
- How often should the filter be replaced? – Replacement frequency depends on feed water quality and operating conditions. Typical service life is 6–12 months, or when the differential pressure reaches 2.0 bar. Regular integrity testing is recommended.
- Is this filter compatible with VHP (Vaporized Hydrogen Peroxide) sterilization? – Yes, the PTFE membrane and stainless steel housing are compatible with VHP, making it suitable for aseptic processing environments.
- Do you provide certificates of compliance or test reports? – We can provide a factory test report for each batch, including bubble point verification. Specific certification (e.g., FDA, USP Class VI) not confirmed; please inquire about custom requirements.
- What end cap configurations are available? – Standard options include 222 O-ring, 226 O-ring, and 0-ring double. Other configurations (e.g., flat end, open end) are available upon request.
- How do I ensure the correct size for my existing housing? – Please provide the housing model or the length, diameter, and connection type (e.g., 2.5” diameter, 20” length, tri-clamp). Our technical team can help match the filter to your system.
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