Preservative DMDM HYDANTOIN CAS No. 6440-58-0
Basic Information
| INCI Adopted Name: | DMDM Hydantoin |
| CAS Registry No.: | 6440-58-0 |
| EINECS No. | 229-222-8 |
| Molecular Formula: | C7H12N2O4 |
| Molecular Weight: | 188.18 |
| Structural Formula: | |
| Synonyms: | DMDMH; 1,3-Dihydroxymethyl-5,5-Dimethylhydantoin |
2. Quality Specification Preservative DMDMH
| Item | Specification |
| Appearance | Colorless to light yellow clear liquid |
| Odor | Odorless or characteristically mild |
| Nitrogen | 7.8~8.6% |
| Specific Gravity( 25ºC) | 1.14~1.17 |
| pH | 5.0~7.0 |
| Total Solids | 54~56% |
| As | 0.001% max |
| Pb | 0.004% max. |
3. Packing
Standard packaging includes the following:
25kg net weight plastic pail
200kg net weight plastic drum
Other package sizes are available upon request.
4. Storage
Avoid freezing. Store at or near room temperature, out of direct sunlight. Keep containers tightly closed when not in use.
Storage at temperatures below 10°C for a long period of time, may cause formation of crystals, requires thawing and mixing prior to use, with no detrimental effect to product quality or efficacy.
5. Period of validity
24 months
6. Properties
Solubility: Very soluble in water; soluble in lower alcohols and glycols.
Antimicrobial Activity: DMDMH is very effective against Gram-positive and Gram-negative bacteria, also provides some protection against yeasts and molds.
Toxicological Data
| Acute oral toxicity LD50 (mice): | >2000mg/kg |
| Eye irritation (rabbits): | Non-irritating at 0.6% aqueous solution |
| Primary skin irritation (rabbits): | Non-irritating at 0.6% aqueous solution |
7. Applications
The active ingredient, preservative DMDM Hydantoin, is permitted for use in cosmetic and
personal care products in the USA and the EU to a maximum concentration of 0.6%.
Our product is compatible with essentially all cosmetic ingredients, such as surfactants, emulsifiers, proteins, aloe and amines. Preservative DMDMH is an excellent preservative for both leave-on and rinse-off products such as shampoos, creams, lotions, bubble baths, rinses, wipes and towelettes.
It is easy to handle, very stable and cost-effective. The recommended use level is 0.1~0.6% by weight of product as supplied.
Preservative DMDMH exhibits an excellent synergistic preservative effect in combination with Iodopropynyl Butylcarbamate (IPBC), Parabens andIsothiazolinones. It is stable over a wide range of pH and temperature conditions. It does not discolor product when combined with additives or by changes in pH. It can be added at a wide range of temperatures from ambient to elevated 80ºC.
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