Norovirus Rapid Test

Noroviruses are a genetically diverse genus of single-stranded RNA, non-enveloped viruses in the Caliciviridae family.The known viruses in the genus are all considered to be the strains of a single species called Norwalk virus. The viruses are transmitted by fecally contaminated food or water; by person-to-person contact;and via aerosolization of the virus and subsequent contamination of surfaces. Noroviruses are the most common cause of viral gastroenteritis in humans, and affect people of all ages.

The test uses new homogenous immunochromatographic system with gold particules. It is a ready to use test which only needs a faecal sample dilution with the supplied ready to use dilution buffer. Specificity is ensured by using a monoclonal antibody conjugated with gold particules and directed against specific human norovirus GII or GI antigens. The immunochromatographic stick is coated with a monoclonal immunoreagent specific for norovirus GII or GI antigen. Liquid sample and gold conjugate both migrate by capillarity and reach the first specific anti-norovirus GI . If norovirus GI is present in the sample, it is blocked and immunoreaction appears as a red-pink line. As sample still migrates, it reaches the second specific reagent line against norovirus GII,  then migrate to the non specific anti-mouse IgG which gives rise to a third red-pink line. This line indicates that the chromatography has been developed without hindrance. It appears also with negative samples.