Home > Products > Polypeptide > 98% Injectable Polypeptide Hormones Hexarelin CAS 140703-51-1 HEX Examorelin For Fat Loss & Cutting Cycles
98% Injectable Polypeptide Hormones Hexarelin CAS 140703-51-1 HEX Examorelin For Fat Loss & Cutting Cycles
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Product Details
Brand Name: | NanJian | Place of Origin: | China | Model Number: | 140703-51-1 |
Product Description
98%Injectable Polypeptide Hormones Hexarelin CAS 140703-51-1 HEX Examorelin ForFat Loss & Cutting Cycles
Quick Details:
Hexarelin
Sequence:His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2
Molecular formula: C47H58N12O6
MW : 887.04022
CASnumber: 140703-51-1
MS:
PubChem: CID 5464109
Synonyms: Hexarelin Acetate, HEX,Examorelin
HS Code : 2937190090
Appearance : White Powder
Purity : 98%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8℃ preservation
Manufacturer : Hezhong
Usage : A synthetic can promote GHrelease six peptide, clinically used in the treatment of growth hormonesecretion deficiency.
Description:
Growthhormone secretagogue receptor is a G protein-coupled receptor that bindsghrelin and plays a role in energy homeostasis and regulation of body weight.
Hexarelinis a six-amino acid peptide. Studies have shown that hexarelin is actually moreeffective and longer lasting than growth hormone releasing hormone (GHRH). Itis also known that GHRP-6 has a synergistic effect with GHRH, causing a fargreater release than either of these substances alone. By combining GHRP-6 withHexarelin, a more potent GH releasing peptide combination is created than everheard of. The potential clinical usefulness of these GH releasing hexapeptidesis also reinforced by observations that long-term administration produceselevations in circulating IGF-1 concentrations. Long term treatment with GHRP-6similarly has been shown to elevate serum IGF-1 as well as IGF-bindingprotein-3 concentrations and promote linear growth.
Application:
Ghrelinis an appetite-regulating factor secreted from peripheral organs that isinvolved in regulation of energy homoeostasis via binding to the receptorresulting in the secretion of growth hormone by the pituitary gland. Thepathway activated by binding of ghrelin to the growth hormone secretagoguereceptor, GHSR1a, regulatesthe activation of the downstream mitogen-activated protein kinase, Akt, nitricoxide synthase, and AMPK cascades in different cellular systems. One of theimportant features of GHSR1adisplays constitutive activity possessing basal activity in the absence of anagonist, resulting in a high degree of receptor internalization as well as ofsignaling activity.Inverse agonists for the ghrelin receptor could beparticularly interesting for the treatment of obesity.This activity seems toprovide a tonic signal required for the development of normal height, probablythrough an effect on the GH axis.
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