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Help CenterBFS Plastic Ampoule Blowing, Filling and Sealing Machine Pharmaceutical Machinery
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Pharmaceutical Machinery
Specifications
2.Frequency variable speeds.
3.Plastic Bottle Forming, Filling and Sealing 3 in 1
4.Meet cGMP.
Blow-Fill-Seal Technique
The Blow Fill Seal Technique has been developed so that formation of the container, filling and
sealing takes place in a single machine under a controlled environment that enables the packaging
of a pharmaceutical liquid in an aseptic manner.
The following picture show the major phases in the integrated packaging of parenteral solutions using the AFP® system.
Aseptic packaging process
As the container is made, filled and sealed within a single machine and the process is protected using a sterile air shower and additionally, all process media (solution, air etc.) are sterile filtered, the
chance of contamination is very remote. Adding to the fact that during the whole cycle, open
containers remain exposed to the clean room air for less than 1.5 seconds, the Blow-Fill-Seal technology becomes the process of choice where contamination of particle matter and microbial contamination is a primary concern.
Product Description
In order to meet the different customers' requirements, SPM has developed an extensive machine program for bottle and ampoule manufacturing including machines with one mould and two moulds.
The machine can fill the plastic container parenterals such as Large Volume Parenterals (LVP),Small Volume Parenterals (SVP) and Eye, Ear, Nose Care Products.
Technology Advantage
Machine separation between filling and mechanical side (dark/white side technology)
Grade A at point of fill,and aseptic design (CIP/SIP)
Up to 20'000 units/hour capacity
Volumes ranging from 0.1 mL to more than 1000 mL
Precision time-pressure-dosing
FDA CFR21 Part11 compliant
In-house container development, prototyping, and contract manufacturing
Product Description
| Product serie | Number of Cavitie | Container Siz | Containers/Hou |
| AFP2 | 20(0.4-3mL) | 0.4-20 | 6000(0.4-3mL) |
| AFP3 | 30(0.4-3mL) | 0.4-20 | 9000(0.4-3mL) |
| AFPL | 11(180mL) | 180-1000mL | 2400(180mL) |
AFP® Blow-Fill-Seal machines has strict design standard and operator-friendly ,equipment with lowest wear, highest process repeatability and reliability, thus meeting all current pharmaceutical regulations of the Health Authorities.
About SPM
Shanghai Pharmaceutical Machinery Co. Ltd. (SPM) is recognized as a major pharmacy equipment manufacturer and supplier. Our company is founded in Shanghai, China, with a base of 20 years
of prior experience in the pharmaceutical industry. This has allowed us to expand our business in a
well-planned manner. We now offer a comprehensive line of quality pharmaceutical machines at
competitive prices. In addition, we can undertake turnkey projects for conceptual design, process
design, water treatment solutions, cleanroom design, etc.
SPM Products
Our products fall into four categories, which are solid preparation machinery,iquid-injection processing
machinery, pharmaceutical packaging machinery, and laboratory instruments. Some of our primary products
are pulverizers, blenders, granulators, sterilizing machines, blister packing machines, encasing machines, air
compressors, and tablet testing instruments. Our solid preparation equipment and liquid processing equipmen,which are corrosion resistant, highly effective, safe, and easy to use, are utilized in countless applications.
For example, our rotary tablet press presses granular materials into tablets, our capsule filling machine is
suitable for filling powdered or granular materials into capsules, and our freeze drying machine is mainly
used for the cryodrying of blood products, vaccines, antibiotics, and biological products. For more product
applications, please see our product page to find a complete list of our pharmaceutical machinery.
Projects
Customer Service
Our excellent customer service also includes the installation of our machines. To ensure smooth
performance, we also provide a one year warranty, and a spare set of wearing parts to our customers.
If any difficulty occurs, we will supply free spare parts and even on-site service, upon request.
Please contact us to help you with your particular spare parts of pharmaceutical equipment.
Industries Served
At SPM, we focus on fabricating efficient and technically sound pharmaceutical machines that meet or exceed our customers' expectations. Our vast product selection caters to numerous industries, worldwide. Some of the areas we serve are
- Food Industry
- Pharmaceutical Industry
- Chemical Industry
- Electronic Industry
- Ceramic Industry
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