PLLA (Medical level) for internal fixators

Chemical name

Poly(L-lactide)

Product Model

PL

Chemical formula

(C₆H₈O₄)_n

CAS registry number

33135-50-1

Chemical Structure

Instructions: Poly(L-lactide) is a kind of biodegradable materials and with good bioabsorbability and biocompatibility. The degradation of Poly(L-lactide) has two steps: first, Poly(L-lactide) is hydrolyzed into Lactic acid; second, the lactic acid turns into pyruvic acid under the function of lactate dehydrogenase, and then enters into mitochondria and is completely oxidized and decomposed to give carbon dioxide and water.

The product which is made from poly(L-lactide) has good biocompatibility. After degradation in the body, the product is excreted by metabolism and It has not harm and side effect to the human body. Therefore our products are currently widely used in the field of medicine, such as the one-time infusion equipment, medical surgical suture, drug delivery carriers, tissue engineering scaffolds, bone anchors, injectable microcapsules, microspheres,implants, elastomer materials for organ support, etc

Text item

Quality index

Appearance

White powder or particles

M_V(Viscosity molecular weight)

6-1000 thousand

IV (Intrinsic viscosity)

0.3-11 dL/g

Specific Rotation (Impregnant: benzene)

≤ -150°

Glass Transition Temperature

> 60°C

Melting Point(DSC(10℃/min))

> 170 °C

ResidualMonomers

<1%

Residual Solvents

<0.5%

Extractable Heavy Metals

< 10 ppm

Stannum (Catalyst)

<200ppm

Density

1.2-1.3g/cm³

Ash Content :

< 0.1%

Model

IV Range

dL/g

M_V Range

ten thousand

PL-05

0.30-0.75

0.6-2.0

PL-10

0.75-1.25

2.0-4.0

PL-15

1.25-1.75

4.0-6.4

PL-20

1.75-2.25

6.4-9.0

PL-25

2.25-3.00

9.0-13.3

PL-35

3.00-4.25

13.3-21.5

PL-50

4.25-6.00

21.5-34.4

PL-70

6.00-8.25

34.4-53.2

PL-95

8.25-11.25

53.2-81.4

PL-00

>11.25

>81.40