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Caulis Sinomenii Extract Sinomenine Hydrochloride

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Negotiable MOQ: 1 Kilogram (Price negotiable depending on order volume and customization)
Key Specifications
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Type:
Herbal Extract
Variety:
Other, Caulis Sinomenii
Form:
Powder
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Ningbo Tianhong Biotech Co., Ltd.
Payment & Shipping
Payment Methods:
Port of Shipment:
Ningbo/Shanghai
Delivery Detail:
Delivery time depends on order quantity.

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Type Herbal Extract
Variety Other, Caulis Sinomenii
Form Powder
Part Other, stem
Extraction Type Liquid-Solid Extraction
Packaging Drum, Vacuum Packed
Place of Origin Zhejiang, China
Grade Pharmaceutical Grade
Brand Name Tian hong
Model Number CSE

Specifications

Caulis Sinomenii Extract:
Appearance:White powder
Specification:Sinomenine Hydrochloride(98%)

Caulis Sinomenii  Extract:
 
Indications and Usage
 
Caulis Sinomenii Extracts Activate DA/NE Transporter and Inhibit 5HT Transporter | Caulis Sinomenii; dopamine; norepinephrine; serotonin; reuptake modulator; transporter | Caulis Sinomenii (QFT) has analgesic, sedative, and anxiolytic-like actions, and is proven effective for improving drug dependence that is known to be associated with abnormal monoaminergic transmission. We assessed whether QFT would be biologically active in functionally regulating monoamine transporters using CHO cells expressing dopamine transporter (DAT), norepinephrine transporter (NET), or serotonin transporter (SERT) (i.e. D8, N1, or S6 cells, respectively). Here, we showed that its primary extracts, such as QA, QC, QE, QD, and QB (QFT ethanol, chloroform, ethyl acetate, alkaloid-free chloroform, and alkaloid-containing chloroform extract, respectively), and secondary extracts, such as QE-2, -3, -5, -7, QD-1, -2, -3, -4, -5, and QB-1, -2, -3, -4, -5 (fractioned from QE, QD, and QB, respectively), in differing degrees, either increased DA/NE uptake by corresponding D8/N1 cells or decreased 5HT uptake by S6 cells; wherein, QE-2, QD-3, and QE-7 were potent DAME uptake activators while both QE-7 and QB-5 were potent 5HT uptake inhibitors. Furthermore, the enhancement of DA/NE uptake was dependent of DAT/NET activity, and the inhibition of 5HT uptake was typical of competition. Thus, QFT extracts, especially QE-2 and QE-7 (both with stronger potencies), are novel monoamine transporter modulators functioning as DAT/NET activators and/or SERT inhibitors, and would likely improve neuropsychological disorders through regulating monoamine transporters. Exp Biol Med 234:976-985, 2009
 
Package:
1kg/bag, 5kg/bag, 25kg/drum, double layers plastic bags inside.
 
Storage Situation:
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

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Ningbo Tianhong Biotech Co., Ltd.
Business Type
Manufacturer
Year Established
2010
Factory Size
1,000-3,000 square meters
Total Employees
51 - 100 People
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