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Home > Agriculture & Food > Sap & Extract > Herbal Extract > Cortex Moutan Extract Paeonol

Cortex Moutan Extract Paeonol

Name: Cortex Moutan Extract Paeonol
Brand: Tian hong
SKU: 106222797
Availability: InStock

Cortex Moutan Extract Paeonol thumbnail-1

Negotiable MOQ: 1 Kilogram (Price negotiable depending on order volume and customization)

Key Specifications

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Type:

Herbal Extract

Variety:

Other, Cortex Moutan

Form:

Powder

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Ningbo Tianhong Biotech Co., Ltd.

Payment & Shipping

Payment Methods:

Port of Shipment:

Ningbo/Shanghai

Delivery Detail:

Delivery time depends on order quantity.

Product Details
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Type Herbal Extract

Variety Other, Cortex Moutan

Form Powder

Part Other, stem bark

Extraction Type Liquid-Solid Extraction

Packaging Drum, Vacuum Packed

Place of Origin Zhejiang, China

Grade Pharmaceutical Grade

Brand Name Tian hong

Model Number CME

Cortex Moutan Extract:

Indications and Usage

Moutan Cortex (MCE) has been used in traditional medicine to remove heat from the blood, promote blood circulation and alleviate blood stasis. This study was conducted to evaluate the effects of MCE on regulatory mechanisms of cytokines and nitric oxide (NO) involved in immunological activity of Raw264.7 cells. Cells were pretreated with methanolic extracts of MCE, and further cultured for an appropriate time after lipopolyssacharide (LPS) addition. During the entire experimental period, 0.1 and 0.3 mg ml⁻¹ of MCE had no cytotoxicity. In these concentrations, MCE inhibited the production of NO and prostaglandin E₂ (PGE₂), the expression of inducible NO synthase (iNOS), cyclooxygenase-2 (COX-2) and phosphorylated inhibitor of κBα (p-IκBα), and the activation of nuclear factor κB (NF-κB). MCE also reduced the concentration of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6) in the Raw264.7 cells that were activated by LPS. These results demonstrate that MCE has anti-inflammatory effects through the inhibition of iNOS and COX-2 expression by suppressing the phosphorylation of I-κBα and the activation of NF-κB.

Package:
1kg/bag, 5kg/bag, 25kg/drum, double layers plastic bags inside.

Storage Situation:
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.