GMP Manufacture Supply Natural Chinese Goldthread Rhizome Extract

Specifications

Goldthread root extract
Berberine hydrochloride 5%-98%
Yellow or yellow brown powder
TUV, GMP, ISO

 

 

GMP Manufacture Supply Natural Chinese Goldthread Rhizome Extract 

 

Product Name: Coptis Root extract / Chinese Goldthread Rhizome Extract

Latin Name: Coptis chinensis Franch, Phellodendron chinense Schneid

Part used: root

Active Ingredient: Alkaloids, Berberine Hydrochloride, Berberine Sulphate,Berberine Chloyide, Rhizoma coptidis, berberinum
Appearance: Yellow or yellow brown powder
Specification: 5:1, 10:1, 5%,10% Alkaloids, 5%-98% Berberine Hydrochloride

Test Method: HPLC  

 

CAS NO: 633-65-8 (Berberine hydrochloride)

EINECS NO: 211-195-9

Molecular Formula: C₂₀H₁₈NO₄.Cl

Molecular Weight: 371.82

Structural Formula: 

Melting point: 200ºC

Water solubility: soluble in water.

 

 

Description:

A perennial herb. Leaves basal, lengthily petiolate, glabrous, pinnate; leaflets 12-15 mm. long, oval-lanceolate, incised, the terminal leaflet longer than the others. Peduncle as long or longer than the leaves; bracts resembling leaves. Flowers yellowish white; sepals linear, lanceolate; petals to 10, margin undulate, two-thirds as long as the sepals; carpels to 14. Fruit a pod; seeds cylindrical, inflated at the middle, surface striate lengthwise, chestnut brown.

The rhizome is officinal. It occurs in pieces 5-6 cm. long, often covered with rootlets, the color brownish yellow, interior yellow-orange, the central pith deeper in color. The taste is bitter. The root of the related C. japonica Makino, indigenous to Japan and which commonly adulterates the Chinese market, contains the alkaloids coptisine(C19H15NO5 ; yellowish needles; m.p. 218°; soluble in alkalies; sparingly soluble in alcohol; very slightly soluble in water), worenine ( C20H17NO5 ; yellow crystalline powder; soluble in hot dilute alcohol), and berberine.

Used as bitter stomachic and digestive, and antidysenteric. Dose, 3-7 gm. 

 

 

Main Functions: 

1. It has the function of removing heat and damp, relieving fire and eliminating toxins;

2. It has the function of anti-inflammatory, antibacterial, antiviral, and antigens worm; And it has obvious inhibition to influenza viruses

3. It has the function of relaxing vascular smooth muscle, and anti diarrhea.

4. It has the function of resisting arrhythmia, lowering presue, and regulating blood level

5. With the function of cholagogue, it can increase bile secreted;

6. Having anti cerebral ischemia effect, it can anti-oxygen free radical and reduce cerebral inland.

 

Application:

1. Applied in pharmaceutical and health product field

2. Applied in pharmaceutical field, it is usually added into capsule or tablet to treat vascular disease.

 

 

 

Technological Process:

Raw Material → Immersion in water → Filtering → Purification → Concentration in Vacuum → Killing of Bacteria → Drying → Powder

 

Analysis

Identification	Must Positive	Positive
Appearance	Fine powder	Conforms
Color	Yellow	Conforms
Odor	Odorless	Conforms
Taste	Bitter	Conforms
Particle Size	100% pass 80 mesh	Conforms
Other alkaloid	Must qualified	Conforms
Loss on drying	≤12.0%	10.64%
Sulfated ash	≤0.2%	0.16%
Heavy Metals	≤20ppm	Conforms
Arsenic (As)	≤2ppm	Conforms
Lead (Pb)	≤5ppm	Conforms
Cadmium (Cd)	≤0.3ppm	Conforms
Mercury (Hg)	≤0.2ppm	Conforms
Residual Solvent	≤0.05%	Conforms
Pesticide Residues	Negative	Negative
Total Plate Count	≤1000cfu/g	Conforms
Yeasts & Molds	≤100cfu/g	Conforms
E. coli	Negative	Negative
Salmonella	Negative

 

Package: 1) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 350mm diameter)

2) 1kg/bag (1kg net weight, 1.2kg gross weight, packed in an aluminum foil bag;Outer: paper carton; Inner: double-layer PE)
3)Or at your option. 

Storage: Stored in a cool and dry well-closed container and in ventilated area, kept away from moisture and strong light or high temperature.

Shelf Life: Two years under well Storage situation and stored away from direct sun light.

  

 

Our advantages:

 

1. Our factory was conducted Onsite assessment by TUV Rheinland from Germany. And we have passed the ISO9001, Chinese Health Food GMP.

  

2. We inspect the manufacture process strictly and the quality can be controlled;

  

3. We supply high quality products, reasonable price, prompt delivery

 

4. Or best quality extract with natural and pure. No additives, organically grown