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Botanical Resource: Artemisia annua L
Family Compositae
Part of the Plant Used Whole grass
Molecular formula: C15H22O5
Molecular weight: 282
CAS No.: 63968-64-9
Product Spec.: Artemisinin 99%
Physiological Functions
Artemisinin (qinghaosu) is the antimalarial principle isolated by Chinese scientists from Artemisia annua L. It is a sesquiterpene lactone with a peroxide bridge linkage. Artemisinin is poorly soluble in oils or water but the parent compound has yielded dihydroartemisinin, the oil-soluble derivatives artemether and arteether, and the more water-soluble derivatives sodium artesunate and artelinic acid. These derivatives have more potent blood schizonticidal activity than the parent compound and are the most rapidly effective antimalarial drugs known. They are used for the treatment of severe and uncomplicated malaria. They are not hypnozoiticidal but gametocytocidal activity has been observed.The antimalarial activity of artemisinin and its derivatives is extremely rapid and most patients show clinical improvement within 1-3 days after treatment.
Quality Specification
Analysis Items |
Specifications |
Test Methods |
Assay |
99% Artemisinin |
HPLC |
Identification |
Positive |
Chemical Method/TLC/IR |
Appearance and Color |
Colorless Crystal |
Visual |
Odor |
Characteristic |
Organoleptic |
Taste |
Bitter |
Organoleptic |
Solubility |
Soluble in Ethanol |
Visual |
Melting Point |
150°C-153°C |
CP2005 |
Optical Rotation[a]D20 |
+75-+78 |
Optical Rotator |
Loss on Drying |
NMT 0.5% |
1g/80°C |
Sulphated Ash |
NMT 0.1% |
1g/600-750°C |
Packing & Storage
Packed in paper-drums with two plastic-bags inside. Net Weight: 25kgs/drum.
Storeed in a well-sealed container away from moisture and light.
Shelf Life
2 years if sealed and store away from direct sun light.
Physiological action and applications
- Anti-malaria
- Anti-schistosomiasis
- Anti pathogenicity microorganism
- To tranquilize and ease pain
- Effect on cardiovascular disease
- To mitigate asthma
- Anti-cancer
Side effect and contraindications
It seldom raises aminotransferase index and cause light tetter. A few case has the side effect of light nausea, disgorge, diarrhea, and so on, but can soon resumes without treatment.
Pregnant women at forepart are forbidden to use this product.
Applications
Pharmaceutical stuff
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