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Biodegradable Medical Raw Material Poly(DL-lactide-co-glycolide) (PDLGA for Implant) (medical Level)

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US$ 1,662 - 1,847 MOQ: 1 Kilogram
Key Specifications
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CAS No.:
26780-50-7
Other Names:
Poly(DL-lactide-co-glycolide)
MF:
(C6H8O4)m (C4H4O4)n
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Changchun Foliaplast Bio-Tech Co., Ltd.
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CAS No. 26780-50-7
Other Names Poly(DL-lactide-co-glycolide)
MF (C6H8O4)m (C4H4O4)n
Place of Origin Jilin, China
Type Other, raw materials for medical device or drug sustained delivery
Brand Name Hanggai
Model Number pdlga
Purity 99%

                          PDLGA Specification

 

Chemical name

Poly(DL-lactide-co-glycolide)

 

 

Product Model

PDLG

 

 

Chemical formula

(C6H8O4)m (C4H4O4)n

 

 

CAS registry number

26780-50-7

 

 

Chemical Structure:

 

 

Instructions:

 

 

 

Poly(DL-lactide-co-glycolide) (PDLGA) is produced from lactic acid and glycolic acid. It is non-toxic and has excellent biodegradability, biocompatibility, film or capsule forming ability. PDLGA is widely used in pharmaceutical, medical engineering materials and modern industrial fields. In the United States, PDLGA has been approved by the FDA and is formally included in the United States pharmacopoeia as pharmaceutical materials.

 

 

 

PDLGA is a amorphous polymer. The glass transition temperature (Tg) of PDLGA is 40 - 60 °C. It has been widely used in medical surgical sutures, anti-adhesion membrane, tissue engineering scaffolds and so on. The degradation rate of PDLGA increases with the increase of GA proportion. Different types of PDLGA can be produced using differentmonomer ratio . For example, PDLGA 75:25 indicates that the polymer consists of 75% DL-lactic acid and 25% glycolic acid.

 

 

 

The degradation products of PDLGA are lactic acid and glycolic acid, so they do not have toxic side effects when used as the pharmaceutical and biological materials. PDLGA has been widely used in biomedical fields, such as medical anti-adhesion membrane, skin graft, stitched wound, injectable microcapsules, microspheres, implants, scaffolds for tissue engineering.

 

 

Text item

Quality index

 

 

Appearance

White powder or particles

 

 

LA/GA:

85/15,75/25,70/30,60/40,50/50

 

 

Specific Rotation(,chloroform)

(-10) – (+10) °

 

 

Glass Transition Temperature

48 - 53°C

 

 

Residual Monomers

<1%

 

 

Residual Solvents

<0.5%

 

 

Extractable Heavy Metals

<10 ppm

 

 

Stannum (Catalyst)

<200 ppm

 

 

Density

1.2-1.3 g/cm3

 

 

Sulfate Ash

<0.1%

 

Model

Ratio DL-LA/GA

IV

DL-LA/GA Proportional Range

IV Range

dL/g

PDLG85-03

85/15

0.3

82/18-88/12

0.20-0.40

PDLG85-05

85/15

0.5

82/18-88/12

0.40-0.70

PDLG85-08

85/15

0.8

82/18-88/12

0.70-1.00

PDLG85-12

85/15

1.2

82/18-88/12

1.00-1.40

PDLG85-16

85/15

1.6

82/18-88/12

1.40-1.80

PDLG85-20

85/15

2.0

82/18-88/12

>1.80

PDLG75-03

75/25

0.3

72/28-78/22

0.20-0.40

PDLG75-05

75/25

0.5

72/28-78/22

0.40-0.70

PDLG75-08

75/25

0.8

72/28-78/22

0.70-1.00

PDLG75-12

75/25

1.2

72/28-78/22

1.00-1.40

PDLG75-16

75/25

1.6

72/28-78/22

1.40-1.80

PDLG75-20

75/25

2.0

72/28-78/22

>1.80

PDLG50-03

50/50

0.3

47/53-53/47

0.20-0.40

PDLG50-05

50/50

0.5

47/53-53/47

0.40-0.70

PDLG50-08

50/50

0.8

47/53-53/47

0.70-1.00

PDLG50-12

50/50

1.2

47/53-53/47

1.00-1.40

PDLG50-16

50/50

1.6

47/53-53/47

1.40-1.80

PDLG50-20

50/50

2.0

47/53-53/47

>1.80

 

 

 

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Changchun Foliaplast Bio-Tech Co., Ltd.
Business Type
Manufacturer
Year Established
2015
Factory Size
Below 1,000 square meters
Total Employees
11 - 50 People
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